SAN JOSE, Calif.–( BUSINESS WIRE )– NVIDIA GTC 2026 – HPE (NYSE: HPE) today announced significant innovations to the NVIDIA AI Computing by HPE portfolio focused on large-scale AI factories and supercomputers that enable customers to scale, deploy efficiently, and gain faster time-to-insight. The full-stack AI solutions with NVIDIA include tightly integrated compute, GPUs, networking, liquid cooling, software, and services designed for at-scale and sovereign environments. AI-forward organizations and leading research institutions, including Argonne National Laboratory, HLRS, Hudson River Trading (HRT), and the Korea Institute of Science and Technology Information (KISTI), have chosen HPE AI infrastructure and AI factories with NVIDIA to advance innovation.
HPE brings NVIDIA AI solutions to its industry-leading supercomputing platform
Research laboratories, sovereign entities and large enterprises are rapidly adopting AI to enhance traditional high performance computing (HPC) workloads. For organizations seeking to significantly expedite scientific discovery, HPE is making the following NVIDIA products available on its second-generation exascale-class supercomputing platform designed to unify AI and HPC – the HPE Cray Supercomputing GX5000 .
“Having built the three most powerful, exascale supercomputers in the world, HPE is at the forefront of innovation that brings together cutting-edge AI workloads with traditional HPC to accelerate scientific breakthroughs,” said Trish Damkroger, senior vice president and general manager, HPC & AI Infrastructure Solutions at HPE. “Our continued collaboration with NVIDIA helps customers tap into the high-performance density they need to push the boundaries in the fields of medicine, life sciences, engineering, manufacturing, and more.”
Enhancing HPE AI Factory at-scale and sovereign, co-engineered with NVIDIA
In addition to the enhancements of its industry-leading supercomputing platform 2 , HPE is bolstering the HPE AI Factory portfolio for service providers, sovereign entities, and large enterprises with the NVIDIA Vera Rubin platform and NVIDIA Blackwell architecture.
These solutions are enhanced by a number of HPE and NVIDIA software and services updates that lead to faster AI deployments for customers rolling out large-scale AI projects.
Each of these solutions are built leveraging HPE’s services and expertise in datacenter design and liquid cooling 6 gained through decades of experience building the largest and most energy-efficient supercomputers in the world 7 .
“To realize the potential of AI, enterprises and nations require infrastructure that can handle massive-scale model training and HPC workloads,” said Chris Marriott, vice president, Enterprise Platforms at NVIDIA. “Together, HPE and NVIDIA have developed full-stack AI infrastructure that unite accelerated computing, advanced networking and liquid cooling for faster time-to-insight in at-scale and sovereign environments.”
Read more about HPE and NVIDIA’s sovereign AI customer stories here
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1 HPE internal market research, March 2026
2 HPE has built and delivered the world’s three fastest exascale supercomputers as of November 2025, as validated by the TOP500
3 Top 80 Data Center Engineering Firms for 2025 , BDE, October 2025
4 The Open Compute Project (OCP) defines OCP-inspired products as those that comply with approved OCP specifications or contributions
5 Compared to the HPE ProLiant Compute XD685
6 HPE has more than 300 patents and five decades of experience in direct liquid cooling
7 HPE has built and delivered 6 of the 10 fastest supercomputers in the world and 10 of the 20 most energy-efficient supercomputers in the world as validated by November 2025 TOP500 and Green500 lists